FACULTY OF ARTS AND SCIENCESDEPARTMENT OF BIOLOGICAL SCIENCES: BIOLOGY/MOLECULAR BIOLOGY & GENETICS


Faculty

Prof. Dr. Feride SEVERCAN

Middle East Technical University, Department of Biological Sciences, 06800 Ankara/TURKEY

Office Room: 138

Tel: +90 312 210 5166

Fax: +90 312 210 7976

E - Mail: feride[-at-]metu.edu.tr

Web:

Education: B.Sc. Ankara University, Dept. of Physics Ankara, Turkey; M. A. Rochester Univ. N.Y. U.S.A. Dept. of Physics; Hacettepe Univ., Physics Eng. Dept., Ankara, Turkey


Research Interest: Molecular Biophysics; Cell Biophysics; Ecotoxilogy; Environmental Biophysics


Description of research activities: Spectroscopic (ESR, FTIR, UV/Visible) and calorimetric investigation of

- Structure and Function of Biological Membranes

- Drug-Liposome Interactions

- Protein Structure, Function and Stability

Molecular Investigation of normal and pathological tissues (e.g., diabetes mellitus , epilepsy, Parkinson desease); treatment and protection mechanism of specific drugs.

Biological spectroscopy and calorimetry of biological system characterization including food , plants, microbial and environmental systems

Effect of radiation on biological tissues


Selected Publications:

Cakmak G., Miller L.M., Zorlu F., Severcan F., “Amifostine, a Radioprotectant Agent, Protects Rat Brain Tissue Lipids against Ionizing Radiation Induced Damage: An FTIR Microspectroscopic Imaging Study”, Archives of Biochemistry and Biophysics, 520, 67-73, 2012.

Aksoy C, Guliyev A, Kilic E, Uckan D, Severcan F., “Bone marrow mesenchymal stem cells in patients with beta thalassemia major: Molecular analyses with attenuated total reflection-fourier transform infrared (ATR-FTIR) spectroscopy study as a novel method”,. Stem Cells Dev. 2012 Jan 4. In press PMID:22214206

Bezirci, G. , Akkas, S.B. Rinke, K. , Yildirim, F. , Kalaylioglu, Z., Severcan, F., Beklioglu, M. “Impacts of salinity and fish-exuded kairomone on the survival and macromolecular profile of Daphnia pulex”, Ecotoxicology , 21(2):601-614, 2012.


Ceylan, C., Severcan, F, Ozkul, A Severcan, M Bozoglu, F, Taheri, N “Biophysical and microbiological study of high hydrostatic pressure inactivation of Bovine Viral Diarrheavirus type 1 on serum”, Veterinary Microbiology, 154:266-,2012.

Cakmak G, Zorlu F, Severcan M, and F. Severcan, “Screening of Protective Effect of Amifostine on Radiation-Induced Structural and Functional Variations in Rat Liver Microsomal Membranes by FT-IR Spectroscopy”, Analytical Chemistry, 83 (7) 2438-2444 , 2011.


Graduate program affiliation: Biology, Biotechnology and Biochemistry