Gülay Özcengiz

Professor


+90 (312) 210 5170

ozcengiz[at]metu.edu.tr

Room 225


EDUCATION

 Biology Dept., Manchester University, U.K., 1989-1990

 Biol. Sci. Dept., METU, 1984-1989

 Biol. Sci. Dept., METU, 1981-1983

 Biology Dept, Hacettepe University, 1975-1980


AREA OF RESEARCH

Molecular Microbiology and Genetics: -Omic technologies for Bacillus subtilis to analyse the role of dipeptide antibiotic bacilysin in quorum sensing global regulation; Transcriptional regulation of cephamycin C biosynthetic gene cluster and pathway engineering to improve clavulinic acid and cephamycin C biosynthesis in Streptomyces clavuligerus; Proteomics and immunoproteomics of Bordetella pertussis and development of novel subunit vaccines; Development of OMV-based re-designed vaccine platforms.


SELECTED PUBLICATIONS

Yılmaz, Ç. and Özcengiz G. 2017. Antibiotics: Pharmacokinetics, toxicity, resistance and multidrug efflux pumps. Biochemical Pharmacology. 133: 43-62.


Ünsaldı, E., Kurt-Kızıldoğan, A., Voigt, B., Becher, D. and Özcengiz, G. 2017. Proteome-wide alterations in an industrial clavulanic acid producing strain of Streptomyces clavuligerus. Synthetic and Systems Biotechnology. 2: 39-48.


Yılmaz, Ç., Apak, A., Özcengiz, E. and Özcengiz G. 2016. Immunogenicity and protective efficacy of recombinant iron superoxide dismutase protein from Bordetella pertussis in mice models. Microbiology and Immunology. 60: 717-724.


Özcengiz, G. and Öğülür, İ. 2015. Biochemistry, genetics and regulation of bacilysin biosynthesis and its significance more than an antibiotic. New Biotechnology. 32: 612-619.


Özcengiz G., and Demain A.L. 2013. Recent advances in the biosynthesis of penicillins, cephalosporins and clavams and its regulation. Biotechnology Advances. 31: 287-311.


Last Updated:
02/10/2019 - 17:34